KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL1
All Species:
23.33
Human Site:
S569
Identified Species:
39.49
UniProt:
Q15111
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15111
NP_006217.3
1095
122728
S569
A
E
M
S
R
R
M
S
V
D
Y
N
G
E
Q
Chimpanzee
Pan troglodytes
XP_001169560
1095
122728
S569
A
E
M
S
R
R
M
S
V
D
Y
N
G
E
Q
Rhesus Macaque
Macaca mulatta
XP_001089483
1095
122754
S569
A
E
M
S
R
R
M
S
V
D
Y
N
G
E
Q
Dog
Lupus familis
XP_536020
1096
122535
S570
A
E
M
S
R
R
L
S
V
D
Y
N
G
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3USB7
1096
122654
S570
A
E
M
S
R
R
M
S
G
D
Y
N
G
E
Q
Rat
Rattus norvegicus
Q62688
1096
122754
S570
A
E
M
S
R
R
V
S
G
D
Y
N
G
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
E526
R
V
G
K
E
G
V
E
L
P
N
I
V
P
V
Chicken
Gallus gallus
Q2VRL0
637
72514
Q180
N
T
Y
L
V
S
D
Q
L
I
G
P
S
D
L
Frog
Xenopus laevis
Q32NH8
758
87399
I301
Q
P
L
C
H
Y
F
I
S
S
S
H
N
T
Y
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S327
A
H
Y
Y
I
S
S
S
H
N
T
Y
L
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
A534
G
G
G
A
E
A
E
A
A
A
A
N
Y
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
R534
S
L
A
S
T
T
R
R
K
S
K
R
I
Q
L
Sea Urchin
Strong. purpuratus
XP_001178766
684
77475
I227
D
L
Q
G
K
I
L
I
K
G
K
R
L
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
G412
A
E
T
P
S
V
E
G
Y
I
Q
V
L
Q
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
98.7
96.4
N.A.
94.3
94.1
N.A.
62.9
21.7
24.7
27.9
N.A.
20
N.A.
39
35.8
Protein Similarity:
100
100
99.2
98.5
N.A.
96.6
96.6
N.A.
77.1
34.8
40.4
42.3
N.A.
40.2
N.A.
59.4
48.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
0
0
0
13.3
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
13.3
13.3
26.6
N.A.
20
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
8
8
0
8
0
8
8
8
8
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
0
0
43
0
0
0
8
8
% D
% Glu:
0
50
0
0
15
0
15
8
0
0
0
0
0
43
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
15
8
0
8
0
8
15
8
8
0
43
0
8
% G
% His:
0
8
0
0
8
0
0
0
8
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
15
0
15
0
8
8
0
0
% I
% Lys:
0
0
0
8
8
0
0
0
15
0
15
0
0
0
8
% K
% Leu:
0
15
8
8
0
0
15
0
15
0
0
0
22
0
15
% L
% Met:
0
0
43
0
0
0
29
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
8
8
50
8
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
0
8
0
8
0
15
0
% P
% Gln:
8
0
8
0
0
0
0
8
0
0
8
0
0
15
50
% Q
% Arg:
8
0
0
0
43
43
8
8
0
0
0
15
0
0
0
% R
% Ser:
8
0
0
50
8
15
8
50
8
15
8
0
8
8
0
% S
% Thr:
0
8
8
0
8
8
0
0
0
0
8
0
0
15
0
% T
% Val:
0
8
0
0
8
8
15
0
29
0
0
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
8
0
8
0
0
8
0
43
8
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _